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What are the key clinical features that should raise suspicion for Acute Lymphoblastic Leukaemia (ALL) in a child?
Answer
Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025
Key clinical features that should raise suspicion for acute lymphoblastic leukaemia in a child include:
- General symptoms: Persistent fatigue, unexplained fever, and unexplained and persistent infections 1.
- Haematological signs: Unexplained petechiae, unexplained bleeding or bruising, and pallor 1.
- Lymphatic and organ enlargement: Generalised lymphadenopathy and unexplained hepatosplenomegaly 1.
- Skeletal symptoms: Persistent or unexplained bone pain 1.
Key References
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