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What are the potential complications of untreated Enterobius vermicularis infections in adults?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 16 August 2025

Potential complications of untreated Enterobius vermicularis (threadworm) infections in adults are generally uncommon and not well-documented in UK guidelines. The infection typically causes perianal itching and discomfort but serious complications are rare.

However, persistent untreated infection may lead to secondary bacterial infections due to scratching and skin irritation around the anus.

In rare cases, threadworms can migrate and cause local inflammation in adjacent areas such as the female genital tract, potentially leading to vulvovaginitis or other genital symptoms.

Overall, the main clinical concern is ongoing discomfort and the risk of reinfection or transmission within households rather than severe systemic complications.

Effective treatment with anthelmintics like mebendazole and strict hygiene measures are recommended to prevent persistence and spread of infection.

No specific life-threatening or systemic complications of untreated Enterobius vermicularis infection in adults are described in the UK clinical guidelines.

References: 1

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