What criteria should I use to refer a patient with gallstone-related complications to secondary care?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 14 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Referral criteria for patients with gallstone-related complications to secondary care include:

  • Emergency admission for any person aged 18 or over who is systemically unwell with suspected complications such as acute cholecystitis, cholangitis, or pancreatitis .
  • Urgent referral to gastroenterology or surgical services with biliary expertise for people with known gallstones and jaundice, or clinical suspicion of biliary obstruction indicated by significantly abnormal liver function tests .
  • Referral of all patients diagnosed with symptomatic gallstone disease to a surgeon for consideration of laparoscopic cholecystectomy, with urgency based on clinical judgement .
  • Hospital admission for suspected acute cholecystitis to confirm diagnosis, monitor clinical status, and initiate treatment including intravenous fluids, antibiotics, analgesia, and surgical assessment for cholecystectomy .
  • Referral for bile duct clearance and laparoscopic cholecystectomy in patients with symptomatic or asymptomatic common bile duct stones due to risk of serious complications such as cholangitis or pancreatitis ,.
  • Consideration of percutaneous cholecystostomy for gallbladder empyema when surgery is contraindicated and conservative management fails .
  • Emergency referral if pain from gallstone disease cannot be managed in primary care .

Educational content only. Always verify information and use clinical judgement.