What criteria should I use to decide whether to refer a patient with hematuria for further urological assessment?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 14 August 2025Updated: 14 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

The criteria for referring a patient with haematuria for further urological assessment, particularly via a suspected cancer pathway (2-week wait), depend on the type of haematuria, the patient's age, and associated symptoms ,,,.

  • For Visible Haematuria:
    • Refer people aged 45 years and over using a suspected cancer pathway referral if they have unexplained visible haematuria without a urinary tract infection (UTI) ,,.
    • Refer people aged 45 years and over using a suspected cancer pathway referral if they have visible haematuria that persists or recurs after successful treatment of a UTI ,,,.
    • In men, visible haematuria may prompt consideration of a prostate-specific antigen (PSA) test and digital rectal examination . If PSA levels are above the age-specific threshold along with visible haematuria or other lower urinary tract symptoms, consider a suspected cancer pathway referral for prostate cancer .
  • For Non-Visible Haematuria:
    • Refer people aged 60 years and over using a suspected cancer pathway referral if they have unexplained non-visible haematuria and either dysuria or a raised white cell count on a blood test ,,,.
  • Specific Considerations for Women:
    • If a pregnant woman has persistent haematuria after completing antibiotic treatment for a UTI, seek urgent specialist advice from an obstetrician regarding ongoing management .
    • For women aged 60 years and over with recurrent or persistent unexplained UTIs, consider a non-urgent referral for bladder cancer ,,.
  • General Advice:
    • If there is any uncertainty about the possible underlying cause of haematuria and an urgent specialist referral is not indicated, seek specialist advice about the need for further assessment and/or referral with a urologist or renal physician, based on clinical judgement .

Educational content only. Always verify information and use clinical judgement.