What are the recommended immediate management steps for a patient presenting with suspected bacterial meningitis?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 14 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Immediate management steps for suspected bacterial meningitis:

  • Arrange emergency transfer to hospital immediately by calling 999; do not delay transfer to give antibiotics unless there is a clinically significant delay in transfer ,,.
  • If a clinically significant delay in transfer is expected, administer a single dose of intravenous or intramuscular ceftriaxone or benzylpenicillin as soon as possible outside hospital ,,.
  • Use ceftriaxone as the preferred antibiotic outside hospital due to its higher activity, but benzylpenicillin is an acceptable alternative if ceftriaxone is unavailable ,.
  • Do not give antibiotics outside hospital if the patient has a severe allergy to ceftriaxone or benzylpenicillin; in such cases, withhold antibiotics until hospital admission and specialist advice ,,.
  • Administer antibiotic doses according to age and weight as per BNF guidance: for example, benzylpenicillin 1200 mg for adults and children aged 10 years or over, ceftriaxone 80 mg/kg (max 2000 mg) for children 1 month to 11 years, and 2000 mg for older children and adults ,.
  • Once in hospital, blood cultures and other investigations should be taken before starting intravenous antibiotics, and lumbar puncture performed if safe and without delaying antibiotics .
  • Start intravenous antibiotics within 1 hour of hospital arrival .

Educational content only. Always verify information and use clinical judgement.