What are the recommended lifestyle modifications for patients diagnosed with non-alcoholic fatty liver disease (NAFLD)?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 14 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Advise patients with NAFLD to undertake gradual, sustained weight loss, aiming for a 5-10% reduction over 6 months with a calorie deficit of about 600 kcal/day .

Recommend a Mediterranean diet, which can reduce liver fat even without weight loss .

Encourage water consumption rather than sugar-sweetened beverages .

Advise at least 150-200 minutes of moderate-intensity aerobic exercise per week, spread over 3-5 sessions, as exercise reduces liver fat content .

Offer lifestyle advice on diet and physical activity regardless of BMI, emphasizing the benefits of exercise and healthy eating .

Advise moderation in alcohol intake within national recommended limits, noting that drinking alcohol in moderation might be protective against NAFLD .

Ensure management of associated conditions such as hypertension, hyperlipidaemia, and type 2 diabetes mellitus, as these influence NAFLD progression .

Educational content only. Always verify information and use clinical judgement.