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What are the recommended screening tools for identifying depression in primary care settings?

Answer

Guideline-Aligned (High Confidence)
Generated by iatroX. Developer: Dr Kola Tytler MBBS CertHE MBA MRCGP (General Practitioner).
Last reviewed: 14 August 2025

In primary care settings, the recommended approach to identifying depression begins with two key screening questions: "During the last month, have you often been bothered by feeling down, depressed or hopeless?" and "During the last month, have you often been bothered by having little interest or pleasure in doing things?" These questions serve as initial case-finding tools to alert practitioners to possible depression 1,2.

Following a positive response to either question, if the practitioner is competent to perform a mental health assessment, they should conduct a more detailed review of the person's mental state, including functional, interpersonal, and social difficulties 1. To enhance diagnostic accuracy, especially in patients with chronic physical health problems, three additional questions about feelings of worthlessness, poor concentration, and thoughts of death may be asked 2.

Validated symptom rating scales are recommended to support assessment and monitoring of depression severity and treatment response. The NICE guidelines specifically endorse the use of validated measures such as the Patient Health Questionnaire-9 (PHQ-9) and the Edinburgh Postnatal Depression Scale (EPDS) for perinatal women 1,4,5,6. The PHQ-9 is widely used in primary care for adults, while the EPDS is tailored for antenatal and postnatal depression screening 4,5.

For patients with communication difficulties, alternative approaches such as the Distress Thermometer or obtaining collateral information from family or carers are advised to identify possible depression 1,2.

Recent literature supports the use of these brief screening questions and validated tools in primary care, highlighting their utility in improving detection rates of depression, although under-detection remains a challenge in some settings (Fekadu et al., 2022). Additionally, while bipolar disorder screening tools exist, depression identification in primary care primarily relies on the two-question case-finding method and validated symptom scales (Hoyle et al., 2015).

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This content was generated by iatroX. Always verify information and use clinical judgment.