What are the most effective contraceptive methods available for women with a history of thromboembolic disease?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 14 August 2025Updated: 14 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

For women with a history of venous thromboembolic disease, combined hormonal contraception (CHC), which includes the pill, transdermal patch, or vaginal ring, should not be used due to an unacceptable health risk (UKMEC 4) .

The UK Medical Eligibility Criteria for Contraceptive Use (UKMEC) provides guidance on combined hormonal contraception, progestogen-only contraception, and intrauterine contraception for women with specific medical conditions . While CHC is contraindicated, other hormonal and intrauterine methods of contraception can generally be considered . UKMEC Category 1 indicates no restriction for use, and UKMEC Category 2 means the method can generally be used, with advantages typically outweighing theoretical or proven risks, though more careful follow-up may be required .

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