What are the recommended first-line treatments for adults with chronic constipation in primary care?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 14 August 2025Updated: 14 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Offer a bulk-forming laxative, such as ispaghula, as the first-line treatment for adults with chronic constipation in primary care .

Encourage lifestyle measures including increased dietary fibre intake, adequate fluid intake, and regular activity .

Advise a regular, unhurried toileting routine and responding promptly to the sensation of needing to defecate .

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