What are the current guidelines for diagnosing COVID-19 in primary care settings?

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 14 August 2025Updated: 14 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

For people identified as being at the highest risk of becoming seriously ill from COVID-19 infection, the current guidance recommends performing lateral flow tests for diagnosis .

For individuals presenting with symptoms and signs of an acute respiratory infection (ARI) in primary care settings, clinical assessment is used to make a diagnosis and decide on management . It is important to note that rapid point-of-care microbiological tests or influenza (flu) tests are not routinely offered to determine whether to prescribe antimicrobials for suspected ARIs . The guideline on suspected acute respiratory infection in over 16s specifically states it does not cover people with known COVID-19, directing to other NICE guidelines for managing COVID-19 infection .

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