How should I adjust the management plan for a patient with asthma who is experiencing frequent exacerbations despite adherence to their current treatm

Guideline-aligned answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 14 August 2025Updated: 14 August 2025 Guideline-Aligned (High Confidence) Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Consider reviewing and addressing possible reasons for uncontrolled asthma before further treatment adjustments, such as checking inhaler technique, adherence, and environmental factors .

If control remains suboptimal, consider increasing the dose of inhaled corticosteroids (ICS) or adding a long-acting beta-2 agonist (LABA) or other controller medications, based on individual assessment .

Assess for risk factors for exacerbations, including SABA overuse, recent oral corticosteroid courses, and environmental triggers, and modify management accordingly .

Use a personalised asthma action plan to guide early recognition and response to worsening symptoms, including when to escalate treatment or seek urgent care .

Review inhaler technique and adherence at every consultation, and consider fractional exhaled nitric oxide (FeNO) monitoring to evaluate adherence and inflammation, if available .

If frequent exacerbations persist despite optimized pharmacotherapy, consider referral to a specialist for further assessment and possible escalation of treatment, including biologic therapies if indicated .

Educational content only. Always verify information and use clinical judgement.