Screening tool for depression in adults, and primary care treatment options?

Clinical answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 8 August 2025 Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

Screening tools for depression in adults:

  • Use the two-question screening method: “During the last month, have you often been bothered by feeling down, depressed or hopeless?” and “During the last month, have you often been bothered by having little interest or pleasure in doing things?”

Available treatment options in primary care:

  • Provide evidence-based verbal and written information about depression and its treatment, tailored to the patient's needs
  • Consider developing advance decisions about treatment and review them regularly
  • Support setting up a Lasting Power of Attorney for health and welfare if appropriate
  • Assess severity, previous history, functional impairment, and social factors to inform treatment decisions
  • For mild to moderate depression, low-intensity psychosocial interventions, psychological interventions, or medication can be offered, with referral for further assessment if needed
  • In cases of severe or complex depression, high-intensity psychological interventions, medication, electroconvulsive therapy, or inpatient care may be necessary

Educational content only. Always verify information and use clinical judgement.