Steps for stable angina management in primary care, including first-line anti-an

Clinical answer with reasoning, red flags and references. Clinically reviewed by Dr Kola Tytler MBBS CertHE MBA MRCGP.

Posted: 3 August 2025Updated: 3 August 2025 Clinically Reviewed
Dr Kola Tytler MBBS CertHE MBA MRCGPClinical Lead • iatroX

In primary care, the management of stable angina involves diagnosing the condition based on clinical assessment and risk factors, and providing patient education about the condition, triggers, and treatment options .

First-line anti-anginal medications include a beta blocker or a calcium channel blocker, chosen based on comorbidities, contraindications, and patient preference .

If symptoms are not controlled, consider switching between these two classes or using a combination of a dihydropyridine calcium channel blocker with a beta blocker .

Additional monotherapy options for those intolerant or contraindicated to first-line drugs include a long-acting nitrate, ivabradine, nicorandil, or ranolazine, with decisions guided by comorbidities, contraindications, preferences, and costs .

For secondary prevention, consider aspirin 75 mg daily, ACE inhibitors in diabetics, statins, and blood pressure control, as appropriate .

Referral for revascularisation (CABG or PCI) is considered if symptoms are not satisfactorily controlled with optimal medical therapy, especially if coronary anatomy indicates left main stem disease or proximal three-vessel disease .

Patients should be advised to use short-acting nitrates for symptom relief, with instructions on administration, repeat dosing, and when to seek emergency care .

Educational content only. Always verify information and use clinical judgement.