A 60-year-old man on ICU has severe TBI. The PRx (pressure reactivity index) is consistently +0.4. What does a positive PRx indicate?...

Question

A 60-year-old man on ICU has severe TBI. The PRx (pressure reactivity index) is consistently +0.4. What does a positive PRx indicate?

Accepted Answer

Impaired cerebral autoregulation - ICP passively follows arterial blood pressure changes, meaning cerebral vasculature cannot maintain constant blood flow; associated with worse outcomes; PRx can identify the optimal CPP (CPPopt) where autoregulation is best preserved

Answer

Normal autoregulation

Answer

Monitor fault

Answer

Clinically irrelevant

Answer

Negative PRx indicates impaired autoregulation

uk-fficm MCQ (SBA): PRx - Autoregulation

A 60-year-old man on ICU has severe TBI. The PRx (pressure reactivity index) is consistently +0.4. What does a positive PRx indicate?