A 55-year-old man on ICU has septic shock requiring massive transfusion. The PROPPR trial compared 1:1:1 vs 1:1:2 ratios of blood products. What was t...

Question

A 55-year-old man on ICU has septic shock requiring massive transfusion. The PROPPR trial compared 1:1:1 vs 1:1:2 ratios of blood products. What was the key finding?

Accepted Answer

A 1:1:1 ratio (pRBC:FFP:platelets) achieved haemostasis more frequently and showed a trend towards reduced exsanguination death compared to 1:1:2 - balanced resuscitation prevents dilutional coagulopathy

Answer

No difference between ratios

Answer

Only pRBC matter in massive transfusion

Answer

FFP should never be given

Answer

Platelets are never needed

uk-fficm MCQ (SBA): Massive Transfusion Ratios

A 55-year-old man on ICU has septic shock requiring massive transfusion. The PROPPR trial compared 1:1:1 vs 1:1:2 ratios of blood products. What was the key finding?