A 48-year-old woman on ICU is receiving continuous IV morphine for analgesia. She develops pinpoint pupils, respiratory depression (RR 6/min, SpO2 85%...

Question

A 48-year-old woman on ICU is receiving continuous IV morphine for analgesia. She develops pinpoint pupils, respiratory depression (RR 6/min, SpO2 85%), and decreased consciousness (GCS 7). What is the immediate treatment?

Accepted Answer

IV naloxone 400 mcg IV, titrated to response - reversing opioid-induced respiratory depression while trying to maintain some analgesic effect

Answer

IV flumazenil 0.2 mg

Answer

IV N-acetylcysteine

Answer

Increase the morphine rate

Answer

IV atropine

uk-fficm MCQ (SBA): Opioid Toxicity

A 48-year-old woman on ICU is receiving continuous IV morphine for analgesia. She develops pinpoint pupils, respiratory depression (RR 6/min, SpO2 85%), and decreased consciousness (GCS 7). What is the immediate treatment?