A 60-year-old woman on ICU with liver cirrhosis (Child-Pugh C) requires a CT-guided liver biopsy. Her INR is 2.5 and platelets are 55 × 10⁹/L. What ar...

Question

A 60-year-old woman on ICU with liver cirrhosis (Child-Pugh C) requires a CT-guided liver biopsy. Her INR is 2.5 and platelets are 55 × 10⁹/L. What are the recommended pre-procedural targets for invasive procedures in liver disease according to BSH guidance?

Accepted Answer

For moderate-risk procedures (e.g. liver biopsy), aim for platelets >50 × 10⁹/L and consider fibrinogen >1.5 g/L; the INR is a poor predictor of bleeding risk in liver disease due to rebalanced haemostasis, and routine FFP correction of INR is NOT recommended

Answer

INR must be  150 × 10⁹/L

Answer

No correction is ever needed

Answer

Always give vitamin K 10 mg IV and FFP before any procedure

Answer

Only platelet transfusion is needed if

uk-fficm MCQ (SBA): Pre-Procedural Haemostasis in Liver Disease

A 60-year-old woman on ICU with liver cirrhosis (Child-Pugh C) requires a CT-guided liver biopsy. Her INR is 2.5 and platelets are 55 × 10⁹/L. What are the recommended pre-procedural targets for invasive procedures in liver disease according to BSH guidance?