A 45-year-old man on ICU is being treated with IV amiodarone. He also receives IV levofloxacin for pneumonia. The pharmacist flags a significant drug ...

Question

A 45-year-old man on ICU is being treated with IV amiodarone. He also receives IV levofloxacin for pneumonia. The pharmacist flags a significant drug interaction. What is the specific risk?

Accepted Answer

QT prolongation - both drugs independently prolong the QT interval, and the combination significantly increases the risk of torsades de pointes

Answer

Hepatotoxicity

Answer

Nephrotoxicity

Answer

Serotonin syndrome

Answer

Bleeding

uk-fficm MCQ (SBA): QT Prolongation - Drug Interaction

A 45-year-old man on ICU is being treated with IV amiodarone. He also receives IV levofloxacin for pneumonia. The pharmacist flags a significant drug interaction. What is the specific risk?