A 55-year-old man on ICU has ARDS with a PaO2/FiO2 of 90 mmHg. He is on FiO2 1.0. The team reviews the risk of oxygen toxicity from prolonged high FiO...

Question

A 55-year-old man on ICU has ARDS with a PaO2/FiO2 of 90 mmHg. He is on FiO2 1.0. The team reviews the risk of oxygen toxicity from prolonged high FiO2 exposure. What FiO2 level should be targeted to minimise oxygen toxicity while maintaining adequate oxygenation?

Accepted Answer

FiO2 should be reduced to the lowest level maintaining PaO2 ≥8 kPa (SpO2 ≥88-92%), ideally targeting FiO2 ≤0.6 to reduce absorptive atelectasis and free radical-mediated lung injury

Answer

FiO2 should always remain at 1.0 in ARDS

Answer

FiO2 should be immediately reduced to 0.21

Answer

FiO2 of 0.8 is always safe for unlimited duration

Answer

Oxygen toxicity does not occur in ventilated patients

uk-fficm MCQ (SBA): Oxygen Toxicity

A 55-year-old man on ICU has ARDS with a PaO2/FiO2 of 90 mmHg. He is on FiO2 1.0. The team reviews the risk of oxygen toxicity from prolonged high FiO2 exposure. What FiO2 level should be targeted to minimise oxygen toxicity while maintaining adequate oxygenation?