A 50-year-old man on ICU following a liver transplant develops primary graft non-function. He becomes progressively encephalopathic, coagulopathic (IN...

Question

A 50-year-old man on ICU following a liver transplant develops primary graft non-function. He becomes progressively encephalopathic, coagulopathic (INR 8.5), and develops multi-organ failure. What is the only definitive treatment?

Accepted Answer

Urgent re-transplantation

Answer

Molecular adsorbent recirculating system (MARS) liver support

Answer

High-dose IV N-acetylcysteine

Answer

Plasmapheresis

Answer

Conservative management with supportive care alone

uk-fficm MCQ (SBA): Primary Graft Non-Function

A 50-year-old man on ICU following a liver transplant develops primary graft non-function. He becomes progressively encephalopathic, coagulopathic (INR 8.5), and develops multi-organ failure. What is the only definitive treatment?