A 52-year-old man on ICU develops suspected local anaesthetic systemic toxicity (LAST) during a regional nerve block performed for analgesia. He has s...

Question

A 52-year-old man on ICU develops suspected local anaesthetic systemic toxicity (LAST) during a regional nerve block performed for analgesia. He has seizures and becomes haemodynamically unstable with a wide-complex bradycardia. What is the specific rescue therapy?

Accepted Answer

IV lipid emulsion 20% (Intralipid) - 1.5 mL/kg bolus over 1 minute, followed by infusion at 15 mL/kg/hr

Answer

IV adrenaline bolus 1 mg

Answer

IV calcium gluconate

Answer

IV naloxone

Answer

IV flumazenil

uk-fficm MCQ (SBA): Local Anaesthetic Toxicity

A 52-year-old man on ICU develops suspected local anaesthetic systemic toxicity (LAST) during a regional nerve block performed for analgesia. He has seizures and becomes haemodynamically unstable with a wide-complex bradycardia. What is the specific rescue therapy?