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HardNeurology & SedationSyndrome of the Trephineduk-fficm
A 42-year-old man on ICU with traumatic brain injury has an ICP of 32 mmHg despite first and second-tier medical therapies. The neurosurgical team performs a decompressive craniectomy. Post-operatively, ICP falls to 12 mmHg. On day 3 post-craniectomy, the team notes paradoxical herniation of brain tissue through the craniectomy defect when the patient is positioned upright. What phenomenon is this?