A 55-year-old woman on ICU develops Clostridioides difficile colitis for the second time, 3 weeks after completing a course of oral vancomycin for the...

Question

A 55-year-old woman on ICU develops Clostridioides difficile colitis for the second time, 3 weeks after completing a course of oral vancomycin for the first episode. According to NICE NG199, what is the recommended treatment for a first recurrence?

Accepted Answer

Oral fidaxomicin 200 mg BD for 10 days (if not used for the initial episode) or oral vancomycin in a pulsed/tapered regimen

Answer

Repeat oral metronidazole 400 mg TDS

Answer

IV vancomycin 1 g BD

Answer

Immediate faecal microbiota transplantation

Answer

Oral rifaximin monotherapy

uk-fficm MCQ (SBA): Recurrent C. difficile Infection

A 55-year-old woman on ICU develops Clostridioides difficile colitis for the second time, 3 weeks after completing a course of oral vancomycin for the first episode. According to NICE NG199, what is the recommended treatment for a first recurrence?