A 65-year-old man on ICU has chronic kidney disease (eGFR 15 mL/min) and is prescribed IV co-amoxiclav for a chest infection. The standard dose is 1.2...

Question

A 65-year-old man on ICU has chronic kidney disease (eGFR 15 mL/min) and is prescribed IV co-amoxiclav for a chest infection. The standard dose is 1.2 g TDS. What dose adjustment is recommended?

Accepted Answer

1.2 g BD (extend interval)

Answer

No adjustment needed

Answer

600 mg TDS (reduce dose)

Answer

1.2 g once daily

Answer

Co-amoxiclav is absolutely contraindicated in CKD

uk-fficm MCQ (SBA): Renal Dose Adjustment

A 65-year-old man on ICU has chronic kidney disease (eGFR 15 mL/min) and is prescribed IV co-amoxiclav for a chest infection. The standard dose is 1.2 g TDS. What dose adjustment is recommended?