A 60-year-old man on ICU is diagnosed with brainstem death following a massive intracerebral haemorrhage. His family consents to organ donation (DBD p...

Question

A 60-year-old man on ICU is diagnosed with brainstem death following a massive intracerebral haemorrhage. His family consents to organ donation (DBD pathway). While awaiting the retrieval team, he develops diabetes insipidus with urine output >300 mL/hr, serum sodium 158 mmol/L, and serum osmolality 320 mOsm/kg. What is the most important pharmacological intervention to maintain organ viability?

Accepted Answer

IV desmopressin (DDAVP) to control diabetes insipidus

Answer

IV frusemide to control the polyuria

Answer

IV hydrocortisone to prevent adrenal crisis

Answer

Fluid restriction

Answer

Discontinue all supportive care immediately

uk-fficm MCQ (SBA): Donor Management - Diabetes Insipidus