A 58-year-old man on ICU has severe hospital-acquired pneumonia caused by Acinetobacter baumannii resistant to all standard antibiotics except colisti...

Question

A 58-year-old man on ICU has severe hospital-acquired pneumonia caused by Acinetobacter baumannii resistant to all standard antibiotics except colistin. Colistin IV is commenced. What is the most significant dose-limiting toxicity of IV colistin?

Accepted Answer

Nephrotoxicity

Answer

Hepatotoxicity

Answer

Ototoxicity

Answer

Bone marrow suppression

Answer

Peripheral neuropathy

uk-fficm MCQ (SBA): Antimicrobial Toxicity

A 58-year-old man on ICU has severe hospital-acquired pneumonia caused by Acinetobacter baumannii resistant to all standard antibiotics except colistin. Colistin IV is commenced. What is the most significant dose-limiting toxicity of IV colistin?