A 45-year-old man on ICU has suspected ventilator-associated pneumonia. Tracheal aspirate culture grows Pseudomonas aeruginosa sensitive to meropenem,...

Question

A 45-year-old man on ICU has suspected ventilator-associated pneumonia. Tracheal aspirate culture grows Pseudomonas aeruginosa sensitive to meropenem, ceftazidime, piperacillin/tazobactam, and ciprofloxacin. He has no drug allergies. What is the most appropriate definitive antibiotic?

Accepted Answer

IV ceftazidime 2 g TDS

Answer

IV meropenem 1 g TDS

Answer

IV piperacillin/tazobactam 4.5 g TDS with IV gentamicin

Answer

IV ciprofloxacin 400 mg BD monotherapy

Answer

IV meropenem 2 g TDS plus IV colistin

uk-fficm MCQ (SBA): Ventilator-Associated Pneumonia

A 45-year-old man on ICU has suspected ventilator-associated pneumonia. Tracheal aspirate culture grows Pseudomonas aeruginosa sensitive to meropenem, ceftazidime, piperacillin/tazobactam, and ciprofloxacin. He has no drug allergies. What is the most appropriate definitive antibiotic?