A 48-year-old woman with paracetamol-induced acute liver failure is on ICU. Her INR is 6.5, pH 7.18, lactate 10 mmol/L, creatinine 300 µmol/L, and she...

Question

A 48-year-old woman with paracetamol-induced acute liver failure is on ICU. Her INR is 6.5, pH 7.18, lactate 10 mmol/L, creatinine 300 µmol/L, and she has grade 3 hepatic encephalopathy. According to the King's College Criteria, which of the following combinations indicates the need for urgent liver transplant assessment?

Accepted Answer

pH

Answer

INR >6.5 alone

Answer

Lactate >5 mmol/L alone

Answer

Grade 3 encephalopathy alone

Answer

Creatinine >300 µmol/L alone

uk-fficm MCQ (SBA): Acute Liver Failure