A 55-year-old man on ICU is receiving a continuous infusion of unfractionated heparin (UFH) for treatment of a pulmonary embolism. His APTT ratio is 4...

Question

A 55-year-old man on ICU is receiving a continuous infusion of unfractionated heparin (UFH) for treatment of a pulmonary embolism. His APTT ratio is 4.5 (target 1.5-2.5). He develops significant bleeding from his surgical wound. What is the most appropriate reversal agent?

Accepted Answer

Protamine sulphate

Answer

Fresh frozen plasma (FFP)

Answer

Vitamin K (phytomenadione) 10 mg IV

Answer

Tranexamic acid 1 g IV

Answer

Idarucizumab

uk-fficm MCQ (SBA): Anticoagulation Reversal

A 55-year-old man on ICU is receiving a continuous infusion of unfractionated heparin (UFH) for treatment of a pulmonary embolism. His APTT ratio is 4.5 (target 1.5-2.5). He develops significant bleeding from his surgical wound. What is the most appropriate reversal agent?