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EasyRespiratory & VentilationAcute Exacerbation of COPDuk-fficm
A 72-year-old man is admitted to ICU with an acute exacerbation of COPD. He is commenced on NIV via full-face mask: IPAP 18 cmH2O, EPAP 5 cmH2O, FiO2 0.28. After 2 hours, ABG shows: pH 7.30, PaO2 8.5 kPa, PaCO2 8.5 kPa, HCO3 32 mmol/L, BE +4. Pre-NIV ABG was: pH 7.25, PaCO2 9.5 kPa. He is alert and cooperative. What is the most appropriate action?