A 70-year-old man with mild AD (MMSE 22) has sick sinus syndrome with a permanent pacemaker. Is Donepezil safe?...

Question

A 70-year-old man with mild AD (MMSE 22) has sick sinus syndrome with a permanent pacemaker. Is Donepezil safe?

Accepted Answer

Yes - the pacemaker protects against clinically significant bradycardia, though monitoring is advisable

Answer

No - absolutely contraindicated with cardiac conduction abnormality

Answer

Yes - Donepezil has no cardiac effects

Answer

No - only IV route in cardiac patients

Answer

Replace with Memantine as first-line

uk-dgm MCQ (SBA): Donepezil with Pacemaker