A 75-year-old woman with a history of osteoporosis, previous vertebral fracture, and CKD stage 4 (eGFR 20) needs bone protection therapy. She cannot t...

Question

A 75-year-old woman with a history of osteoporosis, previous vertebral fracture, and CKD stage 4 (eGFR 20) needs bone protection therapy. She cannot tolerate oral bisphosphonates. Her corrected calcium is 2.35 mmol/L and vitamin D is adequate. What is the MOST appropriate bone protection agent?

Accepted Answer

Denosumab 60 mg subcutaneously every 6 months

Answer

Alendronic acid 70 mg weekly

Answer

Intravenous Zoledronic acid 5 mg annually

Answer

Teriparatide 20 micrograms daily

Answer

Strontium ranelate 2 g daily

uk-dgm MCQ (SBA): Bone Protection in Severe CKD - Denosumab

A 75-year-old woman with a history of osteoporosis, previous vertebral fracture, and CKD stage 4 (eGFR 20) needs bone protection therapy. She cannot tolerate oral bisphosphonates. Her corrected calcium is 2.35 mmol/L and vitamin D is adequate. What is the MOST appropriate bone protection agent?