uk-dgm MCQ (SBA): Clarithromycin-Carbamazepine CYP3A4 Interaction

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HardPolypharmacy & PrescribingClarithromycin-Carbamazepine CYP3A4 Interactionuk-dgm

A 82-year-old man with a CFS of 5 is admitted with delirium. He has a background of well-controlled epilepsy on Carbamazepine 400 mg BD. During his delirium workup, his Carbamazepine level is found to be subtherapeutic despite good adherence. He was recently started on Clarithromycin for a chest infection. What is the MOST likely explanation?

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uk-dgm MCQ: Clarithromycin-Carbamazepine CYP3A4 Interaction — Answer &