A 78-year-old man with chronic pain has been taking Co-dydramol (Dihydrocodeine 10 mg / Paracetamol 500 mg) two tablets QDS for 2 years. He reports th...

Question

A 78-year-old man with chronic pain has been taking Co-dydramol (Dihydrocodeine 10 mg / Paracetamol 500 mg) two tablets QDS for 2 years. He reports the pain is no longer well-controlled and has been taking 3 tablets QDS for the past month. What is the MOST concerning risk of his current practice?

Accepted Answer

Paracetamol toxicity - he is now taking 6 g of Paracetamol daily (3 tablets QDS = 12 tablets = 6 g), which exceeds the maximum daily dose of 4 g and puts him at risk of hepatotoxicity

Answer

Dihydrocodeine addiction

Answer

Constipation only

Answer

Nausea only

Answer

Renal impairment from dihydrocodeine

uk-dgm MCQ (SBA): Paracetamol Toxicity from Compound Analgesic Overuse

A 78-year-old man with chronic pain has been taking Co-dydramol (Dihydrocodeine 10 mg / Paracetamol 500 mg) two tablets QDS for 2 years. He reports the pain is no longer well-controlled and has been taking 3 tablets QDS for the past month. What is the MOST concerning risk of his current practice?