A 79-year-old woman with a CFS of 5 has been identified as having an anticholinergic burden (ACB) score of 8 from her medication regimen: Amitriptylin...

Question

A 79-year-old woman with a CFS of 5 has been identified as having an anticholinergic burden (ACB) score of 8 from her medication regimen: Amitriptyline 25 mg (ACB 3), Oxybutynin 5 mg BD (ACB 3), and Chlorphenamine 4 mg at night (ACB 2, taken for itching). She reports dizziness, dry mouth, constipation, blurred vision, and forgetfulness. What is the SINGLE most impactful action to reduce her anticholinergic burden?

Accepted Answer

Stop Amitriptyline

Answer

Stop Chlorphenamine

Answer

Stop Oxybutynin and switch to Mirabegron for overactive bladder

Answer

Stop all three simultaneously

Answer

Add Donepezil to counteract the anticholinergic effects

uk-dgm MCQ (SBA): Reducing Anticholinergic Burden - Prioritisation