A 77-year-old man with a CFS of 4 has been referred to the memory clinic. He has a 12-month history of cognitive decline with prominent visual halluci...

Question

A 77-year-old man with a CFS of 4 has been referred to the memory clinic. He has a 12-month history of cognitive decline with prominent visual hallucinations, fluctuating alertness, and mild Parkinsonian features. He also experiences autonomic dysfunction (constipation, postural dizziness). His MoCA is 20/30. The consultant suspects Lewy body dementia. What investigation would BEST support this diagnosis?

Accepted Answer

123I-FP-CIT SPECT (DaTSCAN) showing reduced dopaminergic uptake in the basal ganglia

Answer

Lumbar puncture for Alzheimer's biomarkers (amyloid and tau)

Answer

CT head with contrast

Answer

Electroencephalogram (EEG)

Answer

Serum ceruloplasmin level

uk-dgm MCQ (SBA): DaTSCAN in Lewy Body Dementia Diagnosis