A 78-year-old woman has been prescribed Rivaroxaban 20 mg once daily for atrial fibrillation. She takes it in the morning on an empty stomach. She pre...

Question

A 78-year-old woman has been prescribed Rivaroxaban 20 mg once daily for atrial fibrillation. She takes it in the morning on an empty stomach. She presents with recurrent epistaxis and bruising. Her anti-Xa level is subtherapeutic. What is the MOST likely explanation?

Accepted Answer

Rivaroxaban 20 mg should be taken WITH FOOD as bioavailability is significantly reduced when taken on an empty stomach

Answer

She is non-adherent to her medication

Answer

She needs a higher dose of Rivaroxaban

Answer

She has developed an antibody against Rivaroxaban

Answer

The Rivaroxaban is expired

uk-dgm MCQ (SBA): Rivaroxaban - Food Requirement for Absorption

A 78-year-old woman has been prescribed Rivaroxaban 20 mg once daily for atrial fibrillation. She takes it in the morning on an empty stomach. She presents with recurrent epistaxis and bruising. Her anti-Xa level is subtherapeutic. What is the MOST likely explanation?