uk-dgm MCQ (SBA): First-Line C. difficile Treatment - Oral Vancomycin
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ModerateInfection in Older PeopleFirst-Line C. difficile Treatment - Oral Vancomycinuk-dgm
A 84-year-old man with a CFS of 5 and chronic obstructive pulmonary disease is admitted with an infective exacerbation. He is started on Amoxicillin 500 mg TDS and Prednisolone 30 mg daily. On day 4, he develops profuse watery diarrhoea (>6 episodes per day), abdominal cramping, and a temperature of 37.8°C. Stool sample returns positive for Clostridioides difficile toxin. According to NICE NG199, what is the MOST appropriate first-line treatment for this first episode?