A 78-year-old woman with mild cognitive impairment and a CFS of 4 is found to have a haemoglobin of 96 g/L with a mean cell volume (MCV) of 112 fL. Sh...

Question

A 78-year-old woman with mild cognitive impairment and a CFS of 4 is found to have a haemoglobin of 96 g/L with a mean cell volume (MCV) of 112 fL. She has no GI symptoms. She takes Metformin 1 g BD for type 2 diabetes and Omeprazole 20 mg daily. What is the MOST likely cause of her macrocytic anaemia?

Accepted Answer

Vitamin B12 deficiency secondary to long-term Metformin and PPI use

Answer

Iron deficiency anaemia

Answer

Folate deficiency from poor diet

Answer

Anaemia of chronic disease

Answer

Hypothyroidism

uk-dgm MCQ (SBA): Metformin and PPI-Induced B12 Deficiency