A 77-year-old man with stable angina, hypertension, and osteoarthritis is prescribed Ibuprofen 400 mg TDS by his physiotherapist for acute knee pain. ...

Question

A 77-year-old man with stable angina, hypertension, and osteoarthritis is prescribed Ibuprofen 400 mg TDS by his physiotherapist for acute knee pain. He is on Aspirin 75 mg, Atorvastatin 40 mg, and Bisoprolol 2.5 mg. According to STOPP criteria and drug safety guidance, what is the MOST important concern about this prescription?

Accepted Answer

Ibuprofen may reduce the antiplatelet effect of Aspirin and increases cardiovascular and GI bleeding risk in a patient with established cardiovascular disease

Answer

Ibuprofen interacts with Atorvastatin causing rhabdomyolysis

Answer

Ibuprofen causes weight gain

Answer

Ibuprofen interacts with Bisoprolol causing severe bradycardia

Answer

Ibuprofen is safe short-term in cardiovascular disease

uk-dgm MCQ (SBA): NSAID-Aspirin Interaction in Cardiovascular Disease