uk-dgm MCQ (SBA): Methotrexate-Induced Pancytopenia

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ModerateMultimorbidity & Long-term ConditionsMethotrexate-Induced Pancytopeniauk-dgm

A 70-year-old woman with rheumatoid arthritis is on Methotrexate 15 mg weekly, Folic acid 5 mg weekly (day after Methotrexate), and Prednisolone 5 mg daily. She presents with mouth ulcers, sore throat, and bruising. Her FBC shows WCC 1.2 × 10⁹/L, neutrophils 0.4 × 10⁹/L, Hb 98 g/L, platelets 62 × 10⁹/L. What is the MOST likely cause of her pancytopenia?

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uk-dgm MCQ: Methotrexate-Induced Pancytopenia — Answer & Explanation |