A 73-year-old woman with recently diagnosed mild Alzheimer's disease asks about Galantamine. She has a history of peptic ulcer disease. Her current me...

Question

A 73-year-old woman with recently diagnosed mild Alzheimer's disease asks about Galantamine. She has a history of peptic ulcer disease. Her current medications include Lansoprazole 30 mg and Amlodipine 5 mg. Why is Galantamine potentially problematic in this patient?

Accepted Answer

It increases gastric acid secretion via cholinergic stimulation, which may exacerbate peptic ulcer disease

Answer

It interacts with Amlodipine causing hypotension

Answer

It is contraindicated with proton pump inhibitors

Answer

It causes severe hepatotoxicity

Answer

It worsens hypertension

uk-dgm MCQ (SBA): AChEI Risk in Peptic Ulcer Disease

A 73-year-old woman with recently diagnosed mild Alzheimer's disease asks about Galantamine. She has a history of peptic ulcer disease. Her current medications include Lansoprazole 30 mg and Amlodipine 5 mg. Why is Galantamine potentially problematic in this patient?