A 82-year-old woman with moderate Alzheimer's disease on Donepezil 10 mg daily presents with new-onset faecal incontinence. She has no diarrhoea and n...

Question

A 82-year-old woman with moderate Alzheimer's disease on Donepezil 10 mg daily presents with new-onset faecal incontinence. She has no diarrhoea and no GI pathology on investigation. What is the MOST likely medication-related cause?

Accepted Answer

Donepezil-related increased cholinergic activity causing increased gut motility and loose stools

Answer

Paracetamol-related hepatotoxicity

Answer

Statin-related GI side effects

Answer

Amlodipine-related constipation with overflow

Answer

Vitamin D-related hypercalcaemia

uk-dgm MCQ (SBA): Donepezil-Induced Faecal Incontinence

A 82-year-old woman with moderate Alzheimer's disease on Donepezil 10 mg daily presents with new-onset faecal incontinence. She has no diarrhoea and no GI pathology on investigation. What is the MOST likely medication-related cause?