A 74-year-old woman with a past history of recurrent depression is currently well on Sertraline 100 mg daily. She asks her GP how long she should cont...

Question

A 74-year-old woman with a past history of recurrent depression is currently well on Sertraline 100 mg daily. She asks her GP how long she should continue her antidepressant. She has had three episodes of depression over the past 10 years. According to NICE CG90, what is the MOST appropriate advice?

Accepted Answer

She should continue for at least 2 years and potentially long-term given her recurrent episodes

Answer

She should stop Sertraline now as she is well

Answer

She should continue for at least 6 months after remission then stop

Answer

She should switch to Mirtazapine for maintenance as it is safer long-term

Answer

She should take Sertraline every other day to taper slowly

uk-dgm MCQ (SBA): Antidepressant Maintenance Duration