A 73-year-old woman presents with acute onset confusion and right-sided hemiplegia. Her family report she had a fall yesterday but did not hit her hea...

Question

A 73-year-old woman presents with acute onset confusion and right-sided hemiplegia. Her family report she had a fall yesterday but did not hit her head. She has been taking Warfarin for atrial fibrillation and her INR today is 5.2. CT head shows a left-sided intracerebral haemorrhage. What is the MOST important immediate pharmacological intervention?

Accepted Answer

Give Vitamin K (Phytomenadione) intravenously and four-factor prothrombin complex concentrate (PCC)

Answer

Give Protamine sulphate intravenously

Answer

Give Tranexamic acid 1 g intravenously

Answer

Stop Warfarin and wait for the INR to self-correct

Answer

Give fresh frozen plasma alone

uk-dgm MCQ (SBA): Warfarin Reversal in Intracerebral Haemorrhage