A 76-year-old woman with osteoporosis and previous hip fracture is intolerant of oral bisphosphonates (severe oesophageal irritation). Her eGFR is 55 ...

Question

A 76-year-old woman with osteoporosis and previous hip fracture is intolerant of oral bisphosphonates (severe oesophageal irritation). Her eGFR is 55 mL/min/1.73m². She is on calcium and vitamin D supplementation. According to NICE NG188, what is the MOST appropriate second-line bone protection therapy?

Accepted Answer

Denosumab 60 mg subcutaneously every 6 months

Answer

Intravenous Zoledronic acid 5 mg annually

Answer

Teriparatide 20 micrograms subcutaneously daily

Answer

Raloxifene 60 mg daily

Answer

Strontium ranelate 2 g daily

uk-dgm MCQ (SBA): Second-Line Osteoporosis Treatment - Denosumab