An 80-year-old woman with recently diagnosed mild Alzheimer's disease (MMSE 22) is started on Donepezil 5 mg daily. After 4 weeks, she tolerates it we...

Question

An 80-year-old woman with recently diagnosed mild Alzheimer's disease (MMSE 22) is started on Donepezil 5 mg daily. After 4 weeks, she tolerates it well. What is the MOST appropriate next step?

Accepted Answer

Increase Donepezil to 10 mg daily after 4-6 weeks if tolerated

Answer

Continue Donepezil 5 mg indefinitely

Answer

Add Memantine 5 mg daily

Answer

Switch to Rivastigmine patch as it is more effective

Answer

Stop Donepezil as MMSE is above 20

uk-dgm MCQ (SBA): Donepezil Dose Titration

An 80-year-old woman with recently diagnosed mild Alzheimer's disease (MMSE 22) is started on Donepezil 5 mg daily. After 4 weeks, she tolerates it well. What is the MOST appropriate next step?