A 70-year-old man with type 2 diabetes and CKD stage 4 (eGFR 22 mL/min/1.73m²) is reviewed for glycaemic management. His HbA1c is 62 mmol/mol. He is c...

Question

A 70-year-old man with type 2 diabetes and CKD stage 4 (eGFR 22 mL/min/1.73m²) is reviewed for glycaemic management. His HbA1c is 62 mmol/mol. He is currently taking Metformin 500 mg BD and Gliclazide 80 mg OD. He is not on insulin. What is the MOST appropriate change to his diabetes medication?

Accepted Answer

Stop Metformin and continue Gliclazide alone

Answer

Increase Metformin to 1 g BD

Answer

Add Sitagliptin 100 mg daily

Answer

Stop Metformin and start Empagliflozin 10 mg daily

Answer

Stop both and start Insulin

uk-dgm MCQ (SBA): Metformin in CKD - Dose Adjustment

A 70-year-old man with type 2 diabetes and CKD stage 4 (eGFR 22 mL/min/1.73m²) is reviewed for glycaemic management. His HbA1c is 62 mmol/mol. He is currently taking Metformin 500 mg BD and Gliclazide 80 mg OD. He is not on insulin. What is the MOST appropriate change to his diabetes medication?