A 83-year-old man with atrial fibrillation is currently on Apixaban 5 mg twice daily. He has a recent blood test showing eGFR 28 mL/min/1.73m² (previo...

Question

A 83-year-old man with atrial fibrillation is currently on Apixaban 5 mg twice daily. He has a recent blood test showing eGFR 28 mL/min/1.73m² (previously 52). His weight is 78 kg and creatinine is 168 µmol/L. What is the MOST appropriate action regarding his anticoagulation?

Accepted Answer

Reduce Apixaban to 2.5 mg twice daily

Answer

Continue Apixaban 5 mg twice daily

Answer

Stop Apixaban and switch to Warfarin

Answer

Stop all anticoagulation due to high bleeding risk

Answer

Reduce Apixaban to 2.5 mg once daily

uk-dgm MCQ (SBA): Apixaban Dose Adjustment in Renal Impairment

A 83-year-old man with atrial fibrillation is currently on Apixaban 5 mg twice daily. He has a recent blood test showing eGFR 28 mL/min/1.73m² (previously 52). His weight is 78 kg and creatinine is 168 µmol/L. What is the MOST appropriate action regarding his anticoagulation?