A patient from Mozambique with HIV (CD4 30) has Histoplasma capsulatum on bone marrow biopsy. What is the first-line treatment?...

Question

A patient from Mozambique with HIV (CD4 30) has Histoplasma capsulatum on bone marrow biopsy. What is the first-line treatment?

Accepted Answer

Induction with IV liposomal amphotericin B (3 mg/kg/day for 2 weeks) followed by oral itraconazole maintenance for at least 12 months

Answer

Fluconazole 2 weeks

Answer

Voriconazole 6 weeks

Answer

Caspofungin

Answer

Co-trimoxazole

uk-dtmh MCQ (SBA): Disseminated Histoplasmosis Treatment